Results
| PMID | 15672963 |
| Gene Name | FGF2 |
| Condition | Endometriosis |
| Association |
Associated |
| Population size | 63 |
| Population details | 63 women with various stages of endometriosis |
| Sex | Female |
| Associated genes | IL-6, b-FGF, IL-8 |
| Other associated phenotypes |
Endometriosis |
|
Clin Exp Obstet Gynecol. 2004;31(4):269-70. Markowska, J| Kowalska, M| Gogacz, M| Lubin, J| Markowski, M| Kaminska, J Karol Marcinkowski University School of Medicine, Poznan, Poland. INTRODUCTION: Abnormal expression of cytokines is considered to be involved in the pathogenesis of endometriosis. MATERIAL AND METHODS: In 63 women with various stages of endometriosis preoperative levels of cytokines, including IL-6, IL-8, BVEGF, b-FGF, of TNF RI and TNF RII were analysed employing ELISA tests (R&D kits). RESULTS: In the sera of endometriosis patients significantly augmented levels of IL-6 and of b-FGF were detected as well as a trend for elevated IL-8 levels. CONCLUSION: Elevated serum levels of cytokines may show poor correspondence to the localized pathological process. Endometriosis would find a stricter reflection in cytokine levels in fluids or tissues of the pelvis minor. Mesh Terms: Adolescent| Adult| Aged| Cytokines/*blood| Endometriosis/*metabolism/pathology/surgery| Female| Humans| Middle Aged|DA 2005/06/29 09:00 |
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